
At Long Island Ketamine Center, we are dedicated to helping patients overcome the challenges of treatment-resistant conditions through intravenous (IV) ketamine infusions.
Led by Ebrahim Sadighim, MD—a physician with 30+ years of experience treating depression and a member of the American Society of Ketamine Physicians (ASKP)—our center combines advanced medicine with compassionate, patient-centered care.
Ketamine is one of today’s most innovative and rapid-acting treatments for mood disorders and chronic pain. Unlike traditional medications that may take weeks to work—or fail altogether—low-dose ketamine infusions can:
Rebalance mood-regulating brain chemicals
Block pain pathways for chronic pain relief
Deliver results often within 24 hours


For those living with depression that doesn’t improve with medication or therapy, ketamine infusions may provide rapid relief and restore hope.

Ketamine helps calm overactive brain pathways, easing persistent anxiety and promoting a greater sense of peace.

By targeting brain circuits linked to fear and trauma, ketamine can reduce flashbacks, hypervigilance, and emotional distress.

Low-dose ketamine works on the nervous system to block pain signals, offering relief from conditions like fibromyalgia and neuropathy.

Ketamine can interrupt obsessive thought patterns and compulsive behaviors, giving patients more control over daily life.

Ketamine infusions may help stabilize mood swings and improve quality of life for individuals with bipolar depression.

Administered in a safe, supportive setting, IV ketamine therapy provides fast, lasting improvements when traditional treatments fall short.
Today completed my daughter’s 6th Ketomine treatment and I cannot say enough about the caring compassionate treatments Dr. Sadighim provided my daughter & myself. My daughter has dramatically improved in less than 2 weeks and we liked him so much we are going to travel from Melville to Great Neck to utilize his expertise going forward. Thank you Dr. Sadighim for your wonderful care and helping my daughter.
Everyone in the office was extremely professional, pleasant, and helpful. The doctor was very helpful; he listened to and discussed everything in order to make the best decision possible, and he knew exactly what he was doing. He provided exactly what I needed, and I am grateful!
This was possibly the most life changing experience I’ve ever had. Before starting infusion therapy I was depressed, anxious and addicted to benzodiazepines (for 6 years). During my last infusion I had an overwhelming feeling that everything will be ok, and from that day forward I started to get myself off the drugs I was addicted to. I whole heartedly believe I could not have done this without infusion therapy. My whole life has changed and I’m happy and finding meaning and purpose in my life. I also believe that going for infusions lead me to veganism. Fast forward to today, I am doing animal rescue and am very happy, and living a drug free life. Ketamine infusion can be an uncomfortable process sometimes but it can also be extremely beautiful and beyond beneficial. I can not recommend this enough
If you’re struggling with depression, anxiety, PTSD, chronic pain, or another condition that hasn’t improved with conventional treatments, ketamine therapy may be the breakthrough you’ve been searching for.
The team at Long Island Ketamine Center is here to answer your questions and guide you every step of the way.
+1 (516) 530-7224
Long Island Ketamine Center 138 Middle Neck Rd, Great Neck, NY 11021
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